Anisotropic and viscoelastic tensile mechanical properties of aponeurosis: Experimentation, modeling, and tissue microstructure
Anisotropic and viscoelastic tensile mechanical properties of aponeurosis: Experimentation, modeling, and tissue microstructure
复制标题
腱膜的各向异性和粘弹性拉伸机械特性：实验、建模和组织微观结构
DOI：
10.1016/j.jmbbm.2020.103889
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发表时间：
2020
影响因子：
3.9
通讯作者：
Wheatley, Benjamin B.
中科院分区：
文献类型：
--
作者：
Grega, Keith L.;Segall, Ruth N.;Vaidya, Anurag J.;Fu, Chong;Wheatley, Benjamin B.
腱膜是肌肉-肌腱单位的坚硬鞘状组成部分，在力的传递和运动中起着至关重要的作用。腱膜在肌肉骨骼功能中的重要性是显而易见的，但迄今为止关于腱膜材料特性的研究相对较少。这项工作的目标是：1）进行拉伸应力松弛试验，2）进行平面双轴试验，3）采用计算建模的数据从1到2，和4）进行扫描电子显微镜，以确定腱膜组织的胶原纤维组织。应力松弛数据的粘弹性建模和统计分析表明，虽然松弛速率在应变水平之间存在统计学差异（p = 0.044），但功能上的松弛行为几乎相同。双轴测试和相关建模强调了腱膜组织的非线性（趾部区域约2-3%应变）和各向异性（纵向线性模量约50 MPa，横向约2.5 MPa）拉伸力学行为。各种本构公式的比较表明，横观各向同性奥格登方法平衡强拟合（拟合优度0.984）与有限数量的参数（5），而损伤建模参数也提供。扫描电子显微镜显示高度对齐的复合结构，部分波浪形胶原纤维与更随机的胶原电缆的腱膜显微结构。未来的工作，扩大微观结构分析，并使用这些数据来通知计算建模将有利于这项工作和该领域。
Aponeuroses are stiff sheath-like components of the muscle-tendon unit that play a vital role in force transmission and thus locomotion. There is clear importance of the aponeurosis in musculoskeletal function, but there have been relatively few studies of aponeurosis material properties to date. The goals of this work were to: 1) perform tensile stress-relaxation tests, 2) perform planar biaxial tests, 3) employ computational modeling to the data from 1 to 2, and 4) perform scanning electron microscopy to determine collagen fibril organization for aponeurosis tissue. Viscoelastic modeling and statistical analysis of stress-relaxation data showed that while relaxation rate differed statistically between strain levels (p = 0.044), functionally the relaxation behavior was nearly the same. Biaxial testing and associated modeling highlighted the nonlinear (toe region of ~2–3% strain) and anisotropic (longitudinal direction linear modulus ~50 MPa, transverse ~2.5 MPa) tensile mechanical behavior of aponeurosis tissue. Comparisons of various constitutive formulations showed that a transversely isotropic Ogden approach balanced strong fitting (goodness of fit 0.984) with a limited number of parameters (five), while damage modeling parameters were also provided. Scanning electron microscopy showed a composite structure of highly aligned, partially wavy collagen fibrils with more random collagen cables for aponeurosis microstructure. Future work to expand microstructural analysis and use these data to inform computational modeling would benefit this work and the field.