Cranial fasciitis resembling infantile fibrosarcoma differentiated by genetic assay
Cranial fasciitis resembling infantile fibrosarcoma differentiated by genetic assay
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通过基因检测鉴别类似于婴儿纤维肉瘤的颅筋膜炎
DOI：
10.1111/j.1346-8138.2010.01161.x
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发表时间：
2011
期刊：
影响因子：
3.1
通讯作者：
Nakayama J
中科院分区：
文献类型：
--
作者：
Imafuku S;Takahashi A;Hashizumi Y;Sasamoto K;Tokumaru R;Iwasaki H;Nakayama J
给编辑的信 根据我们的研究，在英文出版的著作中只报道了 31 个案例。由于其快速生长和浸润性，有时被怀疑为恶性肿瘤。 3 我们在此报告一例组织病理学上类似于婴儿纤维肉瘤的颅筋膜炎病例，以及基因检测在排除恶性肿瘤方面的有用性。一名 5 岁男孩主诉左眉毛上方有硬块。 2个月内肿块迅速增大。他在该地区没有外伤史。经检查，左眉上方有一直径约4厘米、表面有毛细血管扩张的硬块（图1）。主治医生的第一印象是横纹肌肉瘤。计算机断层扫描和超声检查显示额肌有一个相对明确的肿块合并。在手术室全身麻醉下，肿瘤被切除。手术时，额肌边界模糊，肿瘤似乎起源于帽状腱膜。没有看到骨性头骨的侵蚀。肿瘤被切除为肿块，包括覆盖的皮肤和部分额肌。术后观察到面神经额支部分麻痹。
Letters to the Editor our research, there have been only 31 cases reported in the English-language published work. With its rapid growth and infiltrative nature, it is occasionally suspected as a malignant tumor. 3 We herein report a case of cranial fasciitis that histopathologically resembled infantile fibrosarcoma and the usefulness of a genetic assay to exclude malignancy. A 5-year-old boy presented with a complaint of a firm mass above the left eyebrow. The mass enlarged rapidly in 2 months. He had had no history of trauma in the area. Upon examination, a firm mass with telangiectasia on its surface, sized 4 cm in diameter, was observed above the left eyebrow (Fig. 1). The first impression of the physician in charge was a rhabdomyosarcoma. Computed tomography, as well as ultrasonography, revealed a relatively well-defined mass coalescent to the frontalis muscle. The tumor was surgically removed under general anesthesia in an operating room. At surgery, there was a vague demarcation involving the frontalis muscle, and the tumor seemed to originate from the galea aponeurotica. Erosion of the bony skull was not seen. The tumor was resected as a mass including the overlaying skin and a part of the frontalis muscle. Partial palsy of the frontal branch of the facial nerve was observed after the surgery.