Diversity of the vaccine candidate AMA-1 of Plasmodium falciparum
Diversity of the vaccine candidate AMA-1 of Plasmodium falciparum
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DOI：
10.1016/0166-6851(96)02583-2
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发表时间：
1996-04-01
影响因子：
1.5
通讯作者：
Coppel, RL
中科院分区：
文献类型：
--
作者：
Marshall, VM;Zhang, LX;Coppel, RL
测定了5株恶性疟原虫分离株的顶端膜抗原-1 （AMA-1）的氨基酸序列，并与其他6株已知分离株进行了比较。11个序列中有10个序列是不同的，表明循环AMA-1等位基因的总库可能非常大。[核苷酸序列数据提交给GenBank，登录号U33274-80]。
Amino acid sequences of AMA-1 (apical membrane antigen-1) from 5Plasmodium falciparumisolates were determined and compared with those already known from 6 other isolates. 10 of the 11 sequences were shown to be distinct, indicating that the total repertoire of circulating AMA-1 alleles is probably very large. [Nucleotide sequence data submitted to GenBank, accession numbers U33274-80].