Reconstruction of Y-chromosome phylogeny reveals two neolithic expansions of Tibeto-Burman populations
Reconstruction of Y-chromosome phylogeny reveals two neolithic expansions of Tibeto-Burman populations
复制标题
Y染色体系统发育的重建揭示了藏缅人口的两次新石器时代扩张
DOI：
10.1007/s00438-018-1461-2
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发表时间：
2018-10-01
影响因子：
3.1
通讯作者：
Li, Hui
中科院分区：
文献类型：
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作者：
Wang, Ling-Xiang;Lu, Yan;Li, Hui
藏缅族人口在青藏高原的扩散导致了高海拔环境中最大的人类社区，长期以来一直是高海拔适应，考古学，遗传学和语言学研究的焦点。然而，藏缅族人口的起源、多样化和扩张仍存在很大的不确定性。本研究分析了285个藏缅族和东亚其他相关人群的Y染色体序列，其中包括81个新报道的Y染色体序列。我们确定了几个藏缅族特有的父系谱系，这些谱系大多出现在6000年至2500年前。系统发育树和谱系测定都支持这一假设，即藏缅祖先群体的建立是由新石器时代从黄河中游流域的扩张和混合与当地人口在青藏高原上幸存的旧石器时代。此外，根据单倍群的地理分布，我们认为所有现代藏缅人都有两个新石器时代的扩张起源。我们的研究提供了一个清晰的方案，所有藏缅族人群的祖先人口的来源，混合过程和后来的扩散过程。
Diffusion of Tibeto-Burman populations across the Tibetan Plateau led to the largest human community in a high-altitude environment and has long been a focus of research on high-altitude adaptation, archeology, genetics, and linguistics. However, much uncertainty remains regarding the origin, diversification, and expansion of Tibeto-Burman populations. In this study, we analyzed a 7.0M bp region of 285 Y-chromosome sequences, including 81 newly reported ones, from male samples from Tibeto-Burman populations and other related Eastern Asian populations. We identified several paternal lineages specific to Tibeto-Burman populations, and most of these lineages emerged between 6000 and 2500 years ago. A phylogenetic tree and lineage dating both support the hypothesis that the establishment of Tibeto-Burman ancestral groups was triggered by Neolithic expansions from the middle Yellow River Basin and admixtures with local populations on the Tibetan Plateau who survived the Paleolithic Age. Furthermore, according to the geographical distributions of the haplogroups, we propose that there are two Neolithic expansion origins for all modern Tibeto-Burman populations. Our research provides a clear scenario about the sources, admixture process and later diffusion process of the ancestor population of all Tibeto-Burman populations.