Highly pathogenic avian influenza virus subtype H5N1 in Mute swans in the Czech Republic
Highly pathogenic avian influenza virus subtype H5N1 in Mute swans in the Czech Republic
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DOI：
10.1016/j.vetmic.2006.10.004
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发表时间：
2007-02-25
影响因子：
3.3
通讯作者：
Holko, Ivan
中科院分区：
文献类型：
--
作者：
Nagy, Alexander;Machova, Jirina;Holko, Ivan
为了确定捷克共和国野鸟中禽流感病毒的实际流行情况，2006年1月至4月期间进行了广泛的监测。通过聚合酶链式反应、测序和鸡胚培养，对61种禽类的2101个样本进行了甲型流感病毒的检测。在12只鸣天鹅(Cygnus Olor)中检出H5N1亚型禽流感病毒。经鉴定为HPAI(高致病性禽流感)，其血凝素序列与A/Mallard/Italia/835/06和A/土耳其/土耳其/1194/05非常相似。继首宗H5N1个案后，在疫区共收集了约300只野生禽鸟，分别属33个品种，并进行禽流感病毒测试，但没有任何阳性结果。这是捷克共和国首次报告高致病性禽流感亚型H5N1。文中还讨论了天鹅作为禽流感病毒有效载体的潜在作用。(C)2006爱思唯尔B.V.保留所有权利。
In order to determine the actual prevalence of avian influenza viruses (AIV) in wild birds in the Czech Republic extensive surveillance was carried out between January and April 2006. A total of 2101 samples representing 61 bird species were examined for the presence of influenza A by using PCR, sequencing and cultivation on chicken embryos. AIV subtype H5N1 was detected in 12 Mute swans (Cygnus olor). The viruses were determined as HPAI (highly pathogenic avian influenza) and the hemagglutinin sequence was closely similar to A/mallard/Italy/835/06 and A/turkey/Turkey/1194/05. Following the first H5N1 case, about 300 wild birds representing 33 species were collected from the outbreak region and tested for the presence of AIV without any positive result. This is the first report of highly pathogenic avian influenza subtype H5N1 in the Czech Republic. The potential role of swan as an effective vector of avian influenza virus is also discussed. (c) 2006 Elsevier B.V. All rights reserved.