Neural activation associated with corrective saccades during tasks with fixation, pursuit and saccades
Neural activation associated with corrective saccades during tasks with fixation, pursuit and saccades
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DOI：
10.1007/s00221-007-1077-y
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发表时间：
2008-01-01
影响因子：
2
通讯作者：
Greenlee, Mark W.
中科院分区：
文献类型：
--
作者：
Haller, Sven;Fasler, David;Greenlee, Mark W.
矫正性扫视是当实际眼睛位置与期望的眼睛位置不同时重定向凝视的小的眼睛运动。相对于前眼跳、回视眼跳和记忆引导眼跳，矫正眼跳一直被忽视。研究了在注视、追踪或扫视任务中自发发生的校正扫视的fMRI相关性。在fMRI数据采集过程中使用光纤设备进行眼动追踪。使用组合块和事件相关的设计，我们隔离的皮层激活与视觉引导的固定，追求或扫视任务，并比较这些激活与纠正扫视的发生。前下扣带回、双侧额中回和额下回、双侧小脑和小脑的神经元激活最可能与矫正性扫视特别相关。此外，还存在与已建立的亲眼跳网络以及较小程度上的追踪网络的重叠激活。所提出的结果意味着，校正扫视代表一个潜在的系统混淆在眼动研究，特别是因为自发发生的校正扫视的频率显着不同的固定，追求和亲扫视。
Corrective saccades are small eye movements that redirect gaze whenever the actual eye position differs from the desired eye position. In contrast to various forms of saccades including pro-saccades, recentering-saccades or memory guided saccades, corrective saccades have been widely neglected so far. The fMRI correlates of corrective saccades were studied that spontaneously occurred during fixation, pursuit or saccadic tasks. Eyetracking was performed during the fMRI data acquisition with a fiber-optic device. Using a combined block and event-related design, we isolated the cortical activations associated with visually guided fixation, pursuit or saccadic tasks and compared these to the activation associated with the occurrence of corrective saccades. Neuronal activations in anterior inferior cingulate, bilateral middle and inferior frontal gyri, bilateral insula and cerebellum are most likely specifically associated with corrective saccades. Additionally, overlapping activations with the established pro-saccade and, to a lesser extent, pursuit network were present. The presented results imply that corrective saccades represent a potential systematic confound in eye-movement studies, in particular because the frequency of spontaneously occurring corrective saccades significantly differed between fixation, pursuit and pro-saccades.