Evidence for alternative splicing and developmental regulation of the Drosophila melanogaster Mgat2 (N-acetylglucosaminyltransferase II) gene.
Evidence for alternative splicing and developmental regulation of the Drosophila melanogaster Mgat2 (N-acetylglucosaminyltransferase II) gene.
复制标题
果蝇 Mgat2(N-乙酰氨基葡萄糖转移酶 II)基因的选择性剪接和发育调控的证据。
DOI:
10.1016/j.bbrc.2003.11.059
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发表时间:
2003
影响因子:
3.1
通讯作者:
S. Grammenoudi
中科院分区:
文献类型:
--
作者:
S. G. Tsitilou;S. Grammenoudi
We present a molecular study of the Drosophila melanogaster Mgat2 gene that codes for the N-acetylglucosaminyltransferase II. Isolation and analysis of two cDNA clones indicated that the gene is alternatively spliced, generating two transcripts of 3.3 and 2.7kb. Developmental specificity was observed between the two alternative transcripts during the major developmental stages of D. melanogaster. The deduced amino acid sequences of the two proteins show significant homology to the equivalent mammalian proteins, especially in the carboxyterminal region. In situ hybridizations in embryos and embryonic imaginal discs showed that the gene is expressed mainly but not exclusively in the brain.
影响因子:
--
作者:
G. Pfeifer;A. Riggs
通讯作者:
G. Pfeifer;A. Riggs
DOI:
10.1242/dev.121.11.3687
发表时间:
1995
期刊:
Development (Cambridge, England)
影响因子:
--
作者:
Nakato,H;Futch,TA;Selleck,SB
通讯作者:
Selleck,SB