Exploring the evidence base for national and regional policy interventions to combat resistance
Exploring the evidence base for national and regional policy interventions to combat resistance
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DOI：
10.1016/s0140-6736(15)00520-6
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发表时间：
2016-01-16
期刊：
影响因子：
168.9
通讯作者：
Heymann, David L.
中科院分区：
文献类型：
--
作者：
Dar, Osman A.;Hasan, Rumina;Heymann, David L.
现有控制抗菌素耐药性政策的有效性尚未得到充分了解。需要加强证据基础，以便为不同收入水平以及人类健康和动物部门的国家采取有效的政策干预措施提供信息。我们研究了三个政策领域——负责任的使用、监测以及感染预防和控制——并考虑哪一个在国家和地区层面最有效。在不同的部门和不同的政治和监管环境中实施此类政策存在许多复杂性。因此，我们提出政策行动建议，呼吁使用标准化框架、成本效益和普遍性进行全面的政策评估。此类评估对于低收入和中等收入国家以及动物和环境部门尤其重要。我们还倡导“同一个健康”方法，该方法将有助于制定敏感政策，满足各个相关部门的需求，并解决特定国家和地区的关切。
The effectiveness of existing policies to control antimicrobial resistance is not yet fully understood. A strengthened evidence base is needed to inform effective policy interventions across countries with different income levels and the human health and animal sectors. We examine three policy domains-responsible use, surveillance, and infection prevention and control-and consider which will be the most effective at national and regional levels. Many complexities exist in the implementation of such policies across sectors and in varying political and regulatory environments. Therefore, we make recommendations for policy action, calling for comprehensive policy assessments, using standardised frameworks, of cost-effectiveness and generalisability. Such assessments are especially important in low- income and middle-income countries, and in the animal and environmental sectors. We also advocate a One Health approach that will enable the development of sensitive policies, accommodating the needs of each sector involved, and addressing concerns of specific countries and regions.