Effect of Phytoestrogen on Depression and Anxiety in Menopausal Women: A Systematic Review.
Effect of Phytoestrogen on Depression and Anxiety in Menopausal Women: A Systematic Review.
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DOI：
10.6118/jmm.2017.23.3.160
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发表时间：
2017-12
期刊：
影响因子：
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通讯作者：
Fattah A
中科院分区：
文献类型：
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作者：
Fattah A
在这项系统的综述中，评估了草药改善更年期妇女抑郁和焦虑的有效性。分别搜索以下三个数据库：Medline(1966-2017年3月)、Scope us(1990年-2017年3月)和Cochrane图书馆(Cochrane对照试验中央登记；2017)。本次系统评价共纳入9个试验。总体而言，大豆被发现具有有益的影响。此外，小茴香对患有抑郁症和焦虑症的更年期女性有显著的积极影响，但对健康女性没有影响。红三叶草对抑郁和焦虑的影响从显着到不显着不等。此外，卡瓦被发现在200毫克/天的剂量下对抑郁和焦虑有显著的有益效果。我们的研究表明，中草药可以改善更年期妇女的焦虑和抑郁。然而，由于方法学的欠缺，其益处仍然是不确定的。
In this systematic review, the effectiveness of herbal medicines in improving depression and anxiety in menopausal women was assessed. Three following databases were individually searched: MEDLINE (1966-March 2017), SCOPUS (1990-March 2017), and the Cochrane Library (Cochrane Central Register of Controlled Trials; 2017). A total of 9 trials were included in this systematic review. Overall, soy was found to have a beneficial effect. Also, fennel had a significant positive effect on menopausal women with depression and anxiety disorder, but not on healthy women. Red clover showed varying effects ranging from significant to non-significant on depression and anxiety. Moreover, kava was found to have a significant beneficial effect on depression and anxiety at dose of 200 mg/days. Our study demonstrated that herbal medicines could improve anxiety and depression in among menopausal women. However, the beneficial effect still remains indefinite due to the poor methodology.