Porous Ti-6Al-4V alloy fabricated by spark plasma sintering for biornimetic surface modification
Porous Ti-6Al-4V alloy fabricated by spark plasma sintering for biornimetic surface modification
复制标题
放电等离子烧结多孔Ti-6Al-4V合金仿生表面改性
DOI：
10.1002/jbm.b.20004
复制
发表时间：
2004-01-15
影响因子：
3.4
通讯作者：
Asaoka, K
中科院分区：
文献类型：
--
作者：
Kon, M;Hirakata, LM;Asaoka, K
开发了具有生物相容性和生物力学相容性以及高强度的多孔压块。采用放电等离子体烧结工艺制备了Ti-6Al-4V合金球形粉末，并对其进行了水热处理（HTT）和表面改性处理。纯钛的多孔压块被用作参考材料。孔隙率约为30%，压缩强度分别为113和125 MPa的收到的钛合金粉末和那些改性的HTT过程中，分别。钛合金粉末的抗弯强度和弹性模量分别为128-178 MPa和16-18 GPa。将每个压块浸没在模拟体液（SBF）中。通过重量变化测量磷酸钙通过压块的吸附/沉淀量，并通过SEM观察。在SBF中浸泡2周后，用磷酸钙覆盖压坯。钛合金压坯中有大量的磷灰石析出，高温热处理使磷灰石析出量增加。由于磷酸钙是骨骼的矿物质成分，沉淀在压块表面的磷灰石可以吸附蛋白质和/或抗生素等药物。预期当使用所开发的多孔压块时，可以浸渍大量的蛋白质和/或药物。(C)2003 Wiley Periodicals，Inc.
Porous compacts with both biological and biomecbanical compatibilities and high strength were developed. Spherical powders of Ti-6Al-4V alloy, which were either as received or surface modified with the use of calcium ions by hydrothermal treatment (HTT), were fabricated by a spark plasma sintering process. The porous compacts of pure Ti were used as reference materials. Porosity was approximately 30%, and compressive strengths were 113 and 125 MPa for the as-received Ti alloy powders and those modified by the HTT process, respectively. The bending strength and elastic modulus of as-received Ti alloy powders were 128-178 MPa and 16-18 GPa, respectively. Each of the compacts was immersed in simulated body fluid (SBF). The amount of adsorption/precipitation of calcium phosphate through the compacts was measured by weight change and was observed by SEM. The compacts were covered with calcium phosphate after 2 weeks of immersion in SBF. The compacts of Ti alloy had plenty of precipitated apatite crystals, and modification by HTT accumulated more precipitation. Because calcium phosphate is a mineral component of bone, apatite, which is precipitated on the surface of the compacts, could adsorb proteins and/or drugs such as antibiotics. It is expected that a large amount of proteins and/or drugs could be impregnated when the porous compacts developed are used. (C) 2003 Wiley Periodicals, Inc.