Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy.

Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy.
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DOI:
10.1056/nejmra1609337
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发表时间:
2017-11-30
期刊:
The New England journal of medicine
影响因子:
--
通讯作者:
Blazar BR
Blazar BR
中科院分区:
其他
文献类型:
--
作者:
Zeiser R;Blazar BR

文献摘要

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当骨髓捐献者的T细胞在造血细胞移植后3个月内开始攻击宿主时,就会导致急性移植物抗宿主病。这种疾病主要影响皮肤、肝脏和胃肠道,并使用免疫抑制药物进行治疗。
When T cells from a bone marrow donor begin to attack the host within 3 months after hematopoietic-cell transplantation, acute graft-versus-host disease results. The disease mainly affects the skin, liver, and gastrointestinal tract and is treated with immunosuppressive drugs.