DIFFERENTIAL OXIDATION OF SATURATED AND UNSATURATED FATTY-ACIDS INVIVO IN THE RAT
DIFFERENTIAL OXIDATION OF SATURATED AND UNSATURATED FATTY-ACIDS INVIVO IN THE RAT
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DOI：
10.1079/bjn19870046
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发表时间：
1987-05-01
影响因子：
3.6
通讯作者：
CRAWFORD, MA
中科院分区：
文献类型：
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作者：
LEYTON, J;DRURY, PJ;CRAWFORD, MA
1. 月桂酸、肉豆蔻酸、棕榈酸、硬脂酸、油酸、α的氧化速率。-亚麻酸，亚油酸，亚麻,dihomo可以利用。利用放射性同位素示踪技术研究了断奶大鼠在代谢室休息24小时后的-亚麻酸和花生四烯酸。在饱和脂肪酸中，月桂酸（12:0）是最有效的能量底物：饱和脂肪酸的链长越长，氧化速度越慢。3. 油酸（18:1）被氧化的速度非常快，与月桂酸相似。4. 的。在研究的6种必需脂肪酸中，亚油酸（18:2.omega.6）的氧化速度比它的任何代谢物都快，花生四烯酸（20:4.omega.6）的氧化速度最慢。5. 的氧化速率。-亚麻酸（18:3.omega.3）几乎和月桂酸和油酸一样快。
1. The oxidation rates of lauric, myristic, palmitic, stearic, oleic, .alpha.-linolenic, linoleic, .gamma.-linolenic, dihomo-.gamma.-linolenic and arachidonic acids were studied by use of a radioisotope tracer technique in weanling rats at rest in a metabolism chamber over 24 h. 2. Of the saturated fatty acids, lauric acid (12:0) was the most efficient energy substrate: the longer the chain length of the saturated fatty acids, the slower the rate of oxidation. 3. Oleic acid (18:1) was oxidized at a remarkably fast rate, similar to that of lauric acid. 4. Of the .omega.6 essential fatty acids studied, linoleic acid (18:2.omega.6) was oxidized at a faster rate than any of its metabolites, with arachidonic acid (20:4.omega.6) being oxidized at the slowest rate. 5. The rate of oxidation of .gamma.-linolenic acid (18:3.omega.3) was almost as fast as that of lauric and oleic acids.