Distinct control networks for cognition and emotion in the prefrontal cortex
Distinct control networks for cognition and emotion in the prefrontal cortex
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DOI：
10.1016/j.neulet.2009.10.005
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发表时间：
2009-12-25
影响因子：
2.5
通讯作者：
Nyberg, Lars
中科院分区：
文献类型：
--
作者：
Kompus, Kristiina;Hugdahl, Kenneth;Nyberg, Lars
背外侧前额叶皮层（dlPFC）的激活被认为反映了在资源要求的记忆任务中上下文处理的自上而下的偏置控制机制的参与。在这里，我们测试的假设，dlPFC subserves一个类似的功能，也在注意和情绪任务。18名健康的年轻成年人进行了功能性磁共振成像（fMRI）研究，在三个不同的认知领域：听觉注意，情景检索和情绪调节操纵的上下文处理的需求。我们发现，右前额叶皮层对注意和记忆任务中认知需求的增加是共同敏感的。相比之下，情绪任务（重新评价）中的需求增加与腹内侧PFC沿着杏仁核活动减少的活动增加有关。我们的研究发现，不同的前额叶控制网络的认知和情绪控制扩展了以前的分离的认知和情绪在前扣带皮层。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
The activation of dorsolateral prefrontal cortex (dlPFC) has been suggested to reflect the engagement of a control mechanism for top-down biasing of context processing in resource-demanding memory tasks. Here we tested the hypothesis that the dlPFC subserves a similar function also in attention and emotion tasks. 18 healthy young adults were tested in a functional magnetic resonance imaging (fMRI) study where the demands for context processing were manipulated in three different cognitive domains: auditory attention, episodic retrieval, and emotion regulation. We found that the right dlPFC was jointly sensitive to increased cognitive demands in the attention and memory tasks. By contrast, increased demands in the emotion task (reappraisal) were associated with increased activity in ventromedial PFC along with decreased amygdala activity. Our findings of divergent prefrontal control networks for cognitive and emotional control extend previous separations of cognition and emotion in the anterior cingulate cortex. (C) 2009 Elsevier Ireland Ltd. All rights reserved.