Critical buckling length versus persistence length: what governs biofilament conformation?
Critical buckling length versus persistence length: what governs biofilament conformation?
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临界屈曲长度与持久长度：什么决定生物丝构象？
DOI：
10.1103/physrevlett.102.118102
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发表时间：
2009
影响因子：
8.6
通讯作者：
Hwang,Wonmuk
中科院分区：
文献类型：
--
作者：
Lakkaraju,SirishKaushik;Hwang,Wonmuk
我们数值研究了长度依赖于弯曲刚度ofhelices，盘绕线圈，和线性链模型。当长度接近我们所称的临界屈曲长度时，链条似乎变得越来越灵活。这是由于弱的非键吸引力，最终导致屈曲不稳定性和改变链的构象合奏。对于螺旋和卷曲螺旋来说，它远小于它们各自的持续长度，所以它们的构象的定义长度尺度也是如此。这些结果阐明了弱非特异性吸引力的重要性，在生理条件下，许多生物丝是固有的。
We numerically study the length dependence in the bending stiffness ofhelices, coiled coils, and a linear chain model. As the length approaches what we named the critical buckling length, the chain appears to become increasingly more flexible. This is due to weak nonbonded attractions that eventually lead to buckling instability and alter the chain’s conformational ensemble. Forhelices and coiled coils,is much less than their respective persistence lengths, sois the defining length scale for their conformations. These results elucidate the importance of weak nonspecific attractions that are inherent in many biofilaments in physiological conditions.