Recent patterns in gastric cancer: A global overview

Recent patterns in gastric cancer: A global overview
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DOI:
10.1002/ijc.24290
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发表时间:
2009-08-01
影响因子:
6.4
通讯作者:
La Vecchia, Carlo
La Vecchia, Carlo
中科院分区:
医学1区
文献类型:
--
作者:
Bertuccio, Paola;Chatenoud, Liliane;La Vecchia, Carlo

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直到20世纪90年代中期,胃癌一直是全世界癌症死亡的第一原因,尽管几十年来发病率一直在下降,胃癌在北美和大多数北方和西欧已经成为一种相对罕见的癌症,但在东欧、俄罗斯和中美洲和南美洲或东亚的某些地区则不是。我们使用联合点回归分析法分析了1980年至2005年欧洲和世界其他地区的胃癌死亡率,并提供了51个选定登记中心的最新特定部位发病率。在过去十年中,欧洲主要国家的死亡率年变化百分比(APC)约为-3%至-4%。韩国(APC = -4.3%)、澳大利亚(-3.7%)、美国(-3.6%)、日本(-3.5%)、乌克兰(-3%)和俄罗斯联邦(-2.8%)的APC相似。在拉丁美洲,下降幅度较小,但保持不变,智利和巴西的APC约为-1.6%,阿根廷和墨西哥为-2.3%,哥伦比亚为-2.6%。胃底和幽门癌在高发病率和高死亡率地区更常见,并且比贲门癌下降得更多。胃癌死亡率在全球范围内持续稳定下降趋势,即使在中年人群中,因此在不久的将来可能会进一步明显下降。(C)小行星2609
Until the mid-1990s, gastric cancer has been the first cause of cancer death worldwide, although rates had been declining for several decades and gastric cancer has become a relatively rare cancer in North America and in most Northern and Western Europe, but not in Eastern Europe, Russia and selected areas of Central and South America or East Asia. We analyzed gastric cancer mortality in Europe and other areas of the world from 1980 to 2005 using joinpoint regression analysis, and provided updated site-specific incidence rates from 51 selected registries. Over the last decade, the annual percent change (APC) in mortality rate was around -3, -4% for the major European countries. The APC were similar for the Republic of Korea (APC = -4.3%), Australia (-3.7%), the USA (-3.6%), Japan (-3.5%), Ukraine (-3%) and the Russian Federation (-2.8%). In Latin America, the decline was less marked, but constant with APC around -1.6% in Chile and Brazil, -2.3% in Argentina and Mexico and -2.6% in Colombia. Cancers in the fundus and pylorus are more common in high incidence and mortality areas and have been declining more than cardia gastric cancer. Steady downward trends persist in gastric cancer mortality worldwide even in middle aged population, and hence further appreciable declines are likely in the near future. (C) 2609 UICC