The Effect of Tonsillectomy Alone in Adult Obstructive Sleep Apnea
The Effect of Tonsillectomy Alone in Adult Obstructive Sleep Apnea
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DOI：
10.1177/0194599815575721
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发表时间：
2015-05-01
影响因子：
3.4
通讯作者：
O'Connor, Peter D.
中科院分区：
文献类型：
--
作者：
Senchak, Andrew J.;McKinlay, Alex J.;O'Connor, Peter D.
目的探讨扁桃体切除术治疗成人阻塞性睡眠呼吸暂停（OSA）的疗效。一项评估扁桃体肥大的成年人的机构研究，计划将扁桃体切除术作为一项孤立的手术进行。设置美国国防部内的三级医疗中心。计划于2010年10月至2013年7月入组扁桃体切除术。受试者在术前和术后接受体格检查、埃普沃思嗜睡量表、柏林问卷和多导睡眠图。收集的数据包括人口统计学，问卷评分，呼吸暂停低通气指数（AHI），和最低血氧饱和度。最终分析包括19名OSA检测阳性的受试者。平均年龄为27.9岁，平均体重指数为29.6，扁桃体大小中位数为3，最常见的Friedman分期为1。术前AHI范围为每小时5.4至56.4起事件。术后平均AHI从每小时18.0例降低至3.2例，降低了82%。受试者的AHI降低至少50%，
Objective The purpose of this study was to determine the effect of tonsillectomy as a single procedure in the treatment of adult obstructive sleep apnea (OSA).Study Design Prospective multi-institutional study evaluating adults with tonsillar hypertrophy scheduled to undergo tonsillectomy as an isolated surgery.Setting Tertiary care medical centers within the US Department of Defense.Subjects and Methods Adult subjects with tonsillar hypertrophy who were already scheduled for tonsillectomy were enrolled from October 2010 to July 2013. Subjects underwent physical examination, Epworth Sleepiness Scale, Berlin Questionnaire, and polysomnogram before surgery and after. Collected data included demographics, questionnaire scores, apnea-hypopnea index (AHI), and lowest saturation of oxygen.Results A total of 202 consecutive subjects undergoing tonsillectomy were enrolled. The final analysis included 19 subjects testing positive for OSA. The mean age was 27.9 years; mean body mass index, 29.6; median tonsil size, 3; and most frequent Friedman stage, 1. The AHI before surgery ranged from 5.4 to 56.4 events per hour. The mean AHI decreased from 18.0 to 3.2 events per hour after surgery, a reduction of 82%. The responder ratewith subjects achieving at least a 50% reduction of AHI to a value