Phenotypic Heterogeneity in Chronic Obstructive Pulmonary Disease.
Phenotypic Heterogeneity in Chronic Obstructive Pulmonary Disease.
复制标题
慢性阻塞性肺疾病的表型异质性。
DOI：
10.1164/rccm.202102-0293rr
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发表时间：
2022
影响因子：
24.7
通讯作者：
Singla,Sunit
中科院分区：
文献类型：
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作者：
Kaul,Malvika;Krow,Solomon;Tan,Ai-YuiM;Singla,Sunit
慢性阻塞性肺疾病（COPD）的定义是气流限制和症状。长期以来，各种致病性吸入暴露以及对治疗的不同反应都暗示存在显著的COPD表型异质性（1）。在这里，我们回顾了最近发表的三篇论文，这些论文根据肺功能参数、计算机断层扫描（CT）成像特征和血嗜酸性粒细胞计数来表征COPD的表型。
Chronic obstructive pulmonary disease (COPD) is defined by airflow limitation and symptoms. A variety of causative inhalational exposures, as well as differential responses to therapy, have long alluded to the presence of significant COPD phenotypic heterogeneity (1). Here we review three recently published papers that characterize phenotypes of COPD on the basis of spirometric parameters, computed tomography (CT) imaging features, and blood eosinophil counts.■