Harmonizing the Metabolic Syndrome A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity

Harmonizing the Metabolic Syndrome A Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity
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DOI:
10.1161/circulationaha.109.192644
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发表时间:
2009-10-20
期刊:
影响因子:
37.8
通讯作者:
Smith, Sidney C., Jr.
Smith, Sidney C., Jr.
中科院分区:
医学1区
文献类型:
--
作者:
Alberti, K. G. M. M.;Eckel, Robert H.;Smith, Sidney C., Jr.

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心血管疾病和2型糖尿病的一系列危险因素,通常一起发生而不是单独发生,已被称为代谢综合征。危险因素包括血压升高、血脂异常(甘油三酯升高和高密度脂蛋白胆固醇降低)、空腹血糖升高和中心性肥胖。在过去十年中,不同的组织提出了各种诊断标准。最近,这些来自国际糖尿病联盟和美国心脏协会/国家心肺血液研究所。主要差异涉及中心性肥胖的测量,这是国际糖尿病联合会定义中的强制性组成部分,低于美国心脏协会/国家心肺和血液研究所标准,并且具有种族特异性。本文是几个主要组织为统一标准而举行的一次会议的结果。与会者一致认为,不应有一个强制性的组成部分,但腰围测量将继续是一个有用的初步筛选工具。五分之三的异常结果将使一个人有资格患上代谢综合征。除腰围外的所有组成部分都将使用一组切割点,腰围需要进一步研究。在此期间,可以使用国家或地区的腰围分界点。(循环。2009; 120:1640-1645)。
A cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which occur together more often than by chance alone, have become known as the metabolic syndrome. The risk factors include raised blood pressure, dyslipidemia (raised triglycerides and lowered high-density lipoprotein cholesterol), raised fasting glucose, and central obesity. Various diagnostic criteria have been proposed by different organizations over the past decade. Most recently, these have come from the International Diabetes Federation and the American Heart Association/National Heart, Lung, and Blood Institute. The main difference concerns the measure for central obesity, with this being an obligatory component in the International Diabetes Federation definition, lower than in the American Heart Association/National Heart, Lung, and Blood Institute criteria, and ethnic specific. The present article represents the outcome of a meeting between several major organizations in an attempt to unify criteria. It was agreed that there should not be an obligatory component, but that waist measurement would continue to be a useful preliminary screening tool. Three abnormal findings out of 5 would qualify a person for the metabolic syndrome. A single set of cut points would be used for all components except waist circumference, for which further work is required. In the interim, national or regional cut points for waist circumference can be used. (Circulation. 2009; 120: 1640-1645.)