Effects of mutant Drosophila K+ channel subunits on habituation of the olfactory jump response
Effects of mutant Drosophila K+ channel subunits on habituation of the olfactory jump response
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DOI：
10.1080/01677060701247375
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发表时间：
2007-01-01
影响因子：
1.9
通讯作者：
Wu, C.-F.
中科院分区：
文献类型：
--
作者：
Joiner, M. A.;Asztalos, Z.;Wu, C.-F.
用嗅觉跳跃反应分析了果蝇K+通道亚基突变体的习惯化。就像对巨大纤维介导的逃逸反射的生理学分析一样，编码K+通道亚单位的基因座突变对适应嗅觉跳跃反应有明显的影响。慢击和乙醚跳跃的数据表明，在嗅觉跳跃反应和巨大纤维介导的逃逸的习惯化方面，有类似的影响。在嗅觉跳跃试验中，高动力突变体和Shaker突变体的习惯化程度与巨大纤维介导的逃逸反射的缺陷程度截然不同，这表明两种形式的非联想条件反射背后存在不同的控制机制。
The olfactory-jump response assay was used to analyze habituation in Drosophila mutants of potassium (K+) channel subunits. As with physiological assays of the giant fiber-mediated escape reflex, mutations at loci that encode K+ channel subunits have distinct effects on habituating the olfactory-jump response. The data for slowpoke and ether a go-go indicate similar effects on habituation of the olfactory-jump response and the giant fiber-mediated escape. Habituation in the olfactory jump assay in Hyperkinetic and Shaker mutants was drastically different from the degree of defect in the giant fiber-mediated escape reflex, indicating differential control mechanisms underlying the two forms of non-associative conditioning.