A stereoselective synthesis of (4E,7S)-(-)-7-methoxydodec-4-enoic acid
A stereoselective synthesis of (4E,7S)-(-)-7-methoxydodec-4-enoic acid
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DOI：
10.1055/s-2005-918516
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发表时间：
2006-01-18
影响因子：
2.6
通讯作者：
Cao, XP
中科院分区：
文献类型：
--
作者：
Li, Y;Chen, J;Cao, XP
A stereoselective synthesis of (4E,7S)-(-)-7-methoxy dodec-4-enoic acid has been accomplished in eight steps from hex: anal in 24% overall yield. The key steps involved the catalytic asymmetric allylation of hexanal and the coupling reaction of a chiral alkyne and a protected bromide in the presence of t-BuLi.
