Proline-directed protein phosphorylation and cell cycle regulation
Proline-directed protein phosphorylation and cell cycle regulation
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DOI：
10.1016/0955-0674(91)90136-m
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发表时间：
1991-04-01
影响因子：
7.5
通讯作者：
Vulliet, P. Richard
中科院分区：
文献类型：
--
作者：
Hall, Frederick L.;Vulliet, P. Richard
最近的发现集中在控制哺乳动物体细胞周期的C1-S相变的新兴酶学上。这些发现使人们认识到，在分子信号转导中，脯氨酸引导的蛋白质磷酸化的调节作用，并导致了一个推定的原癌基因的鉴定。
Recent discoveries have converged on the emerging enzymology that governs the C1-S phase transition of the mammalian somatic cell cycle. These discoveries have led to an appreciation of the regulatory role of proline-directed protein phosphorylation in molecular signalling, and have resulted in the identification of a putative proto-oncogene.