Performing bone marrow aspiration and biopsy in children: Recommended guidelines
Performing bone marrow aspiration and biopsy in children: Recommended guidelines
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DOI：
10.1093/pch/13.6.499
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发表时间：
2008-07-01
影响因子：
1.9
通讯作者：
Doyle, John
中科院分区：
文献类型：
--
作者：
Abla, Oussama;Friedman, Jeremy;Doyle, John
骨髓穿刺（BMA）和骨髓活检是诊断儿童恶性血液病和非恶性血液病的重要手段。在BMA期间，获得骨髓颗粒用于分析，包括显微镜形态学评价和分类计数。在环钻活检过程中，获得并处理骨髓核心，以评估骨髓细胞构成，并排除实体瘤、淋巴瘤或其他过程对骨髓的影响。这些侵入性手术只能由经过培训的人员按照标准操作技术进行。儿科文献中没有明确的已发表指南。因此，本文的目的是提供指导方针的性能BMAs和骨髓环钻活检的儿童，这将是有用的一般儿科医生和儿科血液学家和肿瘤学家。
Bone marrow aspiration (BMA) and bone marrow trephine biopsy are important procedures for the diagnosis of hematological malignancies and nonmalignant diseases in children. During BMA, bone marrow particles are obtained for analysis including microscopic morphologic evaluations and differential counts. During a trephine biopsy, a core of bone marrow is obtained and processed for the evaluation of marrow cellularity and to rule out marrow involvement by solid tumours, lymphomas or other processes. These invasive procedures should only be performed by a trained individual following a standard operating technique. There are no clear published guidelines in the paediatric literature. Hence, the purpose of the present article is to provide guidelines for the performance of BMAs and bone marrow trephine biopsies in children that will be useful for both general paediatricians and paediatric hematologists and oncologists.