THE TOPOGRAPHY OF THE MESENCEPHALIC AND PONTINE PROJECTIONS FROM THE CINGULATE CORTEX OF THE RAT
THE TOPOGRAPHY OF THE MESENCEPHALIC AND PONTINE PROJECTIONS FROM THE CINGULATE CORTEX OF THE RAT
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DOI：
10.1016/0006-8993(84)91448-3
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发表时间：
1984-01-01
期刊：
影响因子：
2.9
通讯作者：
SRIPANIDKULCHAI, K
中科院分区：
文献类型：
--
作者：
WYSS, JM;SRIPANIDKULCHAI, K
从大鼠中线皮质到中脑和脑桥的投射被确认了几年。使用放射自显影技术的投影的详细分析。在68只大鼠的扣带回皮质的各个节段内注射少量[3H]氨基酸。证实了扣带回脑干投射的存在，并证明了扣带回皮质细胞起源与其脑干内终止区域之间的精确地形关系。皮质的最腹侧和前段（IRa α）投射到中脑导水管周围灰质腹侧、脑桥腹侧核背内侧和外侧被盖区。背前皮质（IRc α）投射到上级丘、中脑导水管周围灰质背外侧和脑桥腹内侧核。中间前皮质投射到中脑导水管周围灰质的背侧和腹侧，轻微投射到上级丘和中腹侧脑桥核。放射下区（IR）皮质的后半部分投射到背外侧导水管周围灰质、上级丘和脑桥腹侧核区域，该区域略位于IR前皮质所占据的终末区的外侧。越来越多的IR β的背侧节。皮质投射到腹侧核的腹侧区域。中线皮质的后部（压后皮质，R）不投射到背侧中脑，但它确实在地形上投射到腹侧脑桥核，位于IR轴突的终末区的外侧。越来越多的R皮质的后部区域投射到腹侧核的更外侧区域，并且越来越多的R皮质的背侧细胞投射到腹侧核的更背侧区域。一个非常精确的地形脑干的预测，这可能是基础的扣带皮层的内脏和躯体运动功能，以及扣带皮层的能力，以调节感觉信息和情绪行为，被证明。
A projection from the rat midline cortex to the midbrain and pons was recognized for several years. A detailed analysis of this projection using the autoradiographic technique is described. Small injections of [3H]amino acids were placed within individual segments of the cingulate cortex in 68 rats. The existence of the cingulo-brainstem projections was reaffirmed and a precise topographical relationship between the cingulate cortex cells of origin and their termination fields within the brainstem was demonstrated. The most ventral and anterior segment of the cortex (IRa.alpha.) projects to the ventral periaqueductal gray, the dorso-medial ventral pontine nuclei and the lateral tegmental region. The dorso-anterior cortex (IRc.alpha.) projects to the superior colliculus, the dorso-lateral periaqueductal gray and the medio-ventral ventral pontine nuclei. The intermediate anterior cortex projects to both dorsal and ventral periaqueductal gray, lightly to the superior colliculus and to the medio-intermediate ventral pontine nuclei. The posterior half of the infraradiata (IR) cortex projects to the dorso-lateral periaqueductal gray, the superior colliculus and the region of the ventral pontine nuclei slightly lateral to the terminal zone occupied by the anterior IR cortex. Increasingly dorsal segments of the IR.beta. cortex project to more increasingly ventral areas of the ventral nuclei. The posterior portion of the midline cortex (retrosplenial cortex, R) does not project to the dorsal midbrain, but it does topographically project to the ventral pontine nuclei, lateral to the terminal zone of the IR axons. Increasingly, posterior regions of the R cortex project to more lateral regions of the ventral nuclei, and increasingly, dorsal cells of the R cortex project to more dorsal regions of the ventral nuclei. A very precise topography of brainstem projections which may underlie the visceral and somatic motor functions of the cingulate cortex, as well as the ability of the cingulate cortex to modulate sensory information and emotional behavior, was demonstrated.