High Blood Pressure Confirmed with 24-Hour Ambulatory Blood Pressure Monitoring in Tanzanian Adolescents Enrolling in a Cohort Study
High Blood Pressure Confirmed with 24-Hour Ambulatory Blood Pressure Monitoring in Tanzanian Adolescents Enrolling in a Cohort Study
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DOI：
10.21203/rs.3.rs-123312/v1
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发表时间：
2020-12
期刊：
影响因子：
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通讯作者：
M. K. Nsanya;P. Ayieko;R. Hashim;Ezekiel Mgema;D. Fitzgerald;S. Kapiga;R. Peck
中科院分区：
文献类型：
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作者：
M. K. Nsanya;P. Ayieko;R. Hashim;Ezekiel Mgema;D. Fitzgerald;S. Kapiga;R. Peck
撒哈拉以南非洲青少年中高血压（BP）的患病率估计差异很大，大多数研究都依赖于自动办公室BP（AOBP）测量。我们的目的是估计高血压的患病率，使用无人值守的AOBP，然后进行24小时动态血压监测（24小时ABPM）进行确认，并确定与确认的高血压相关的因素。2018年4月至8月，从坦桑尼亚姆万扎市随机选择的三所公立学校招募了500名11至15岁的青少年，参加为期2年的前瞻性队列研究。我们获得了三个连续的无人值守AOBP测量。在初始测量时血压高的参与者中获得了后续AOBP测量结果。随访测量值仍然较高的参与者接受了24小时ABPM。在所有500名参与者中，36.6%的人使用第一次AOBP测量时血压较高; 25.6%的人使用第二次和第三次AOBP测量的平均值，10.2%的人使用随访AOBP测量的平均值，并有资格进行24小时ABPM。只有13例（2.6%）证实有高血压，他们没有独特的鉴别特征。白色被毛高血压在非洲青少年中很常见。非洲的心血管健康促进可以通过使用一个无人值守的AOBP在青少年中进行基于学校的高血压筛查来完成
Prevalence estimates for high blood pressure (BP) among adolescents in sub-Saharan Africa vary widely and most studies have relied on attended automated office BP (AOBP) measurements. We aimed to estimate prevalence of high BP using unattended AOBP followed by 24-Hour ambulatory BP monitoring (24-Hour ABPM) for confirmation and to determine factors associated with confirmed high BP. Between April and August 2018, 500 adolescents aged 11 to 15 years were enrolled from three randomly selected public schools in Mwanza city (Tanzania) to participate in a 2-year prospective cohort study. We obtained three consecutive unattended AOBP measurements. Follow-up AOBP measurements were obtained in participants with high BP at initial measurements. Participants whose follow-up measurements remained high underwent 24-Hour ABPM. Of all 500 participants, 36.6% had high BP using first AOBP measurement; 25.6% using average of the second and third AOBP measurements and 10.2% using average of follow-up AOBP measurements and were eligible for 24-Hour ABPM. Only 13(2.6%) had confirmed high BP and they had no unique distinguishing characteristic. White coat hypertension is common among adolescents in Africa. Cardiovascular health promotion in Africa can be done through school-based screening for high BP among adolescents using one unattended AOBP