Sleep-Disordered Breathing: A Risk Factor for Adverse Pregnancy Outcomes?
Sleep-Disordered Breathing: A Risk Factor for Adverse Pregnancy Outcomes?
复制标题
DOI:
10.1055/s-0031-1295658
复制
发表时间:
2012-04-01
影响因子:
2
通讯作者:
Zee, Phyllis C.
中科院分区:
文献类型:
--
作者:
Facco, Francesca L.;Liu, Cici S.;Zee, Phyllis C.
In nonpregnant populations, sleep-disordered breathing (SDB) has been associated with cardiovascular and metabolic disease. Few studies have examined the relationship between SDB and adverse pregnancy outcomes (APO). The objective of this study was to examine the association between SDB and APO. Women who had a delivery as well as an in-laboratory polysomnogram (PSG) were identified. Demographics, PSG results, and pregnancy outcomes were abstracted from the medical record. Absence of SDB was defined as an apnea hypopnea index (AHI) of = 15. The primary outcome was a composite measure of APO: pregnancy-related hypertension, gestational diabetes, or preterm birth = 30) with moderate to severe SDB had the highest rate of APO, 41.7%. SDB, especially moderate to severe disease, may be associated with APO. However, it is unclear if SDB is a risk factor for APO independent of obesity.