Prognostic value of heart rate variability in chronic congestive heart failure (veterans affairs' survival trial of antiarrhythmic therapy in congestive heart failure)

Prognostic value of heart rate variability in chronic congestive heart failure (veterans affairs' survival trial of antiarrhythmic therapy in congestive heart failure)
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DOI:
10.1016/s0002-9149(02)02380-9
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发表时间:
2002-07-01
影响因子:
2.8
通讯作者:
Berger, RD
Berger, RD
中科院分区:
医学3区
文献类型:
--
作者:
Bilchick, KC;Fetics, B;Berger, RD

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尽管心率变异性(HRV)对急性心肌梗死后危险分层的价值已得到证实,但低HRV作为缺血性心肌病患者心源性猝死的预测因子的价值迄今尚未得到令人信服的证实。我们回顾性分析了退伍军人事务部抗充血性心力衰竭生存试验中179例患者的心电图数据,以确定HRV(表示为正常至正常RR间期的SD [SDNN])是否可用于预测总体死亡率和猝死。因为我们的目标是识别高风险患者,我们将HRV最低四分位数的患者与其余患者进行比较。在符合入选标准的127例患者中,SDNN
Although the value of heart rate variability (HRV) for risk stratification after acute myocardial infarction has been demonstrated, the value of low HRV as a predictor of sudden cardiac death in patients with ischemic cardiomyopathy has not been shown convincingly to date. We retrospectively analyzed electrocardiographic data from 179 patients in the Veterans Affairs' Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure to determine if HRV (expressed as the SD of the normal-to-normal RR intervals [SDNN]) would be useful as a predictor of overall mortality and sudden death. Because our goal was to identify high-risk patients, we compared patients in the lowest quartile of HRV with the remaining patients. Among the 127 patients meeting inclusion criteria, SDNN