Clinical potential of diagnostic methods for the rapid diagnosis of Mycoplasma pneumoniae pneumonia in adults
Clinical potential of diagnostic methods for the rapid diagnosis of Mycoplasma pneumoniae pneumonia in adults
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DOI：
10.1007/s10096-010-1107-8
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发表时间：
2011-03-01
影响因子：
4.5
通讯作者：
Oka, M.
中科院分区：
文献类型：
--
作者：
Miyashita, N.;Kawai, Y.;Oka, M.
本研究的目的是评估三种快速诊断方法的准确性和实用性，即ImmunoCard支原体试剂盒、胸部高分辨率计算机断层扫描（HRCT）结果和日本呼吸学会（JRS）评分系统（包括6个参数），用于成人肺炎支原体肺炎的早期推定诊断。我们对四组肺炎同时进行了三种快速诊断方法：68例肺炎支原体肺炎。肺炎链球菌肺炎133例，流感嗜血杆菌肺炎30例，军团菌肺炎20例。ImmunoCard的敏感性和特异性分别为35%和68%，HRCT的敏感性和特异性分别为73%和85%，JRS评分系统的敏感性和特异性分别为83%和90%。在三种快速诊断方法中，JRS评分系统是最有用的工具，用于启动适当的抗生素治疗可能的M。肺炎我们建议M.当JRS评分系统中超过5个参数相关时（99%特异性），应怀疑肺炎性肺炎。如果在JRS评分系统中有三个或四个参数相关，胸部计算机断层扫描（CT）结果有助于M的推定诊断。肺炎
The purpose of the present study was to evaluate the accuracy and usefulness of three rapid diagnostic methods, ImmunoCard Mycoplasma kit, chest high-resolution computed tomography (HRCT) findings, and the Japanese Respiratory Society (JRS) scoring system (including six parameters), for the early presumptive diagnosis of Mycoplasma pneumoniae pneumonia in adults. We performed three rapid diagnostic methods at the same time in four pneumonia groups: 68 cases with M. pneumoniae pneumonia, 133 cases with Streptococcus pneumoniae pneumonia, 30 cases with Haemophilus influenzae pneumonia, and 20 cases with Legionella pneumonia. The sensitivity and specificity were 35% and 68% for ImmunoCard, 73% and 85% with HRCT, and 83% and 90% with the JRS scoring system, respectively. Among the three rapid diagnostic methods, the JRS scoring system was the most useful tool for initiating the administration of adequate antibiotic therapy for probable M. pneumoniae pneumonia. We suggest that M. pneumoniae pneumonia should be suspected when there is a correlation of more than five parameters in the JRS scoring system (99% specificity). If there is a correlation of three or four parameters in the JRS scoring system, chest computed tomography (CT) findings are helpful for the presumptive diagnosis of M. pneumoniae pneumonia.