Pathophysiology, classification, and MRI parallels in microvascular disease of the heart and brain.
Pathophysiology, classification, and MRI parallels in microvascular disease of the heart and brain.
复制标题
心脏和大脑微血管疾病中的病理生理，分类和MRI相似。
DOI：
10.1111/micc.12648
复制
发表时间：
2020-11
期刊：
影响因子：
--
通讯作者：
Nguyen KL
中科院分区：
文献类型：
--
作者：
Thomas MA;Hazany S;Ellingson BM;Hu P;Nguyen KL
Diagnostic imaging technology in vascular disease has long focused on large vessels and the pathologic processes that impact them. With improved diagnostic techniques, investigators are now able to uncover many underlying mechanisms and prognostic factors for microvascular disease. In the heart and brain, these pathologic entities include coronary microvascular disease and cerebral small vessel disease, both of which have significant impact on patients, causing angina, myocardial infarction, heart failure, stroke and dementia. In the current paper we will discuss parallels in pathophysiology, classification, and diagnostic modalities, with a focus on the role of magnetic resonance imaging in microvascular disease of the heart and brain. Novel approaches for streamlined imaging of the cardiac and central nervous systems including the use of intravascular contrast agents such as ferumoxytol are presented and unmet research gaps in diagnostics are summarized.
