A Retrospective Analysis of Gender-Based Difference in Adherence to Influenza Vaccination during the 2018-2019 Season
A Retrospective Analysis of Gender-Based Difference in Adherence to Influenza Vaccination during the 2018-2019 Season
复制标题
DOI：
10.1177/2150132720958532
复制
发表时间：
2020-09-01
影响因子：
3.6
通讯作者：
Valery, Jose Raul
中科院分区：
文献类型：
--
作者：
Applewhite, Andres;Stancampiano, Fernando F.;Valery, Jose Raul
简介：提高普通人群的流感疫苗接种率是降低季节性流感发病率、死亡率和成本的重要而有效的策略。为了优化免疫战略，需要探讨与疫苗接种率下降相关的因素。文献表明，流感疫苗接种率存在性别差异，但仅限于基于人群的调查研究，而且关于哪种性别的疫苗接种率更高也不一致。本研究的目的是评估在2018年至2019年流感季节期间进行年度体检的患者中流感疫苗接种率的性别差异。研究方法：在这项多中心、回顾性病历审查中，共纳入了1193例在2019年4月接受年度体格检查的患者（608例女性和585例男性）。收集基线医学信息，以及人口统计学特征和流感疫苗接种状况。使用多变量logistic回归模型比较男性和女性接受流感疫苗接种的患者比例;估计比值比（OR）。结果如下：在未校正分析（OR = 1.49，P <0.001）和校正了诊所位置、BMI、保险类型和职业等潜在混杂影响的多变量分析（OR = 1.42，P = 0.005）中，女性（62.8%）接种流感疫苗的可能性显著高于男性（53.2%）。有趣的是，与男性相比，在年龄
Introduction: Improving flu vaccination rates in the general population is an important and effective strategy toward reducing morbidity, mortality, and the cost of seasonal influenza. In order to optimize immunization strategies, factors associated with decreased vaccination rates need to be explored. The literature suggests that there is a gender difference in the rate of influenza vaccination but is limited to population-based survey studies and also is inconsistent as to which gender has a higher rate of vaccination. The purpose of this study was to evaluate for a gender-based difference in the rate of influenza vaccination among patients who presented for an annual physical examination during the 2018 to 2019 influenza season. Methods: In this multi-site, retrospective chart review, a total of 1193 patients (608 female and 585 male) who underwent an annual physical examination in April of 2019 were included. Baseline medical information was collected, as well as demographic characteristics and influenza vaccination status. The proportion of patients who underwent influenza vaccination was compared between males and females using multivariable logistic regression models; odds ratios (ORs) were estimated. Results: The likelihood of influenza vaccination was significantly higher in females (62.8%) compared to males (53.2%) in both unadjusted analysis (OR = 1.49,P < .001) and in multivariable analysis adjusting for the potential confounding influences of clinic location, BMI, insurance type, and occupation (OR = 1.42,P = .005). Interestingly, a higher influenza vaccination rate for females compared to males was observed in patients age