Relation of childhood socioeconomic status and family environment to adult metabolic functioning in the CARDIA study
Relation of childhood socioeconomic status and family environment to adult metabolic functioning in the CARDIA study
复制标题
DOI：
10.1097/01.psy.0000188443.48405.eb
复制
发表时间：
2005-11-01
影响因子：
3.3
通讯作者：
Seeman, TE
中科院分区：
文献类型：
--
作者：
Lehman, BJ;Taylor, SE;Seeman, TE
目的：儿童时期的低社会经济地位和充满冲突、忽视或恶劣的家庭环境与成年后身体健康障碍的高发生率有关。本研究的目的是评估一种可能有助于解释这些联系的途径模型，并将它们与青年冠状动脉风险发展(CARDIA)数据库中的代谢功能(MF)联系起来。方法：参加15年CARDIA评估的3225人，年龄33~45岁，完成儿童社会经济状况(SES)、危险的早期家庭环境(RF)、成人心理社会功能(通过抑郁、敌意、积极和消极的社会交往衡量的潜在因素)和成年SES的测量。评估了潜在因子MF的指标，特别是胆固醇、胰岛素、葡萄糖、甘油三酯和腰围。结果：代谢综合征总患病率为9.7%。结构方程模型表明，儿童SES和RF通过与心理因子的关联(标准化路径系数：儿童SES到RF-0.13，RF到心理F 0.44，心理F到MF 0.09，均p&t；0.05)与MF相关，但也直接(从童年SES到MF-0.12，p&t；0.05)，具有良好的整体模型拟合。当这个模型分别针对种族性别分组进行测试时，它最适合白人女性，很适合非裔美国女性和白人男性，但不适合非裔美国男性。结论：这些结果表明，童年自闭症和早期家庭环境通过抑郁、敌意和社交质量差等途径促进新陈代谢功能。
Objective: Low SES and a conflict-ridden, neglectful, or harsh family environment in childhood have been linked to a high rate of physical health disorders in adulthood. The objective of the present investigation was to evaluate a model of the pathways that may help to explain these links and to relate them to metabolic functioning (MF) in the Coronary Artery Risk Development In Young Adults (CARDIA) dataset. Methods: Participants (n = 3225) in the year 15 assessment of CARDIA, age 33 to 45 years, completed measures of childhood socioeconomic status (SES), risky early family environment (RF), adult psychosocial functioning (PsyF, a latent factor measured by depression, hostility, positive and negative social contacts), and adult SES. Indicators of the latent factor MF were assessed, specifically, cholesterol, insulin, glucose, triglycerides, and waist circumference. Results: The overall prevalence of metabolic syndrome was 9.7%. Structural equation modeling indicated that childhood SES and RF are associated with MF via their association with PsyF (standardized path coefficients: childhood SES to RF -0.13, RF to PsyF 0.44, PsyF to MF 0.09, all p < .05), but also directly (coefficient from childhood SES to MF -0.12,p < .05), with good overall model fit. When this model was tested separately for race-sex subgroups, it fit best for white women, fit well for African-American women and white men, but did not fit well for African-American men. Conclusions: These results indicate that childhood SES and early family environment contribute to metabolic functioning through pathways of depression, hostility, and poor quality of social contacts.