When IL-17 gets on your nerves.

When IL-17 gets on your nerves.
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当 IL-17 令您紧张时。

DOI:
10.1016/j.cell.2022.12.048
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发表时间:
2023
期刊:
影响因子:
64.5
通讯作者:
Gaffen,SarahL
Gaffen,SarahL
中科院分区:
生物学1区
文献类型:
--
作者:
Iliev,IliyanD;Lin,Woan-Yu;Gaffen,SarahL

文献摘要

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Microbiota-induced IL-17 production mediates CNS processes and animal behavior. However, its role on the peripheral nervous system (PNS) remains largely unknown. Enamorado et al. demonstrate that commensal-specific Th17 cells are recalled following tissue injury to support local nerve regeneration, a process orchestrated by IL-17 signaling on peripheral neurons.