Comparison of structure extraction methods for in vivo trabecular bone measurements
Comparison of structure extraction methods for in vivo trabecular bone measurements
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DOI：
10.1016/s0895-6111(98)00071-8
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发表时间：
1999-03-01
影响因子：
5.7
通讯作者：
Rüegsegger, P
中科院分区：
文献类型：
--
作者：
Laib, A;Rüegsegger, P
体内小梁骨结构测量最近已成为可用的高分辨率定量计算机断层扫描（3D-QCT）或磁共振成像。本文比较了不同的结构提取和形态测量评价技术，为人体松质骨结构的体内评价提供了潜在的应用前景。考虑到实际体内检查过程的空间分辨率，首先提取结构骨架，然后应用与模型无关的3D技术计算小梁数，然后从密度计体积分数和Tb.N*中得出平均小梁厚度和分离度，可以获得最佳结果。传统的组织形态测量方法基于骨表面积和体积比，并假设一个板模型表现不佳。1999爱思唯尔科学有限公司版权所有。
In vivo trabecular bone structure measurements have become available recently using high resolution quantitative computed tomography (3D-QCT) or magnetic resonance imaging. In this work different structure extraction and morphometric evaluation techniques are compared, which are of potential use for in vivo assessment of human cancellous bone structure. Given the spatial resolution of actual in vivo examination procedures, best results are obtained by extracting first the skeleton of the structure and applying model independent 3D techniques to calculate trabecular number, then deriving mean trabecular thickness and separation from densitometric hone volume fraction and Tb.N*. Traditional histomorphometric methods based on bone surface and volume ratios and assuming a plate model performed less well. (C) 1999 Elsevier Science Ltd. All rights reserved.