Laryngeal cancer: Diagnosis and preoperative work-up

Laryngeal cancer: Diagnosis and preoperative work-up
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DOI:
10.1016/j.otc.2008.01.016
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发表时间:
2008-08-01
影响因子:
1.7
通讯作者:
Kim, Young J.
Kim, Young J.
中科院分区:
医学3区
文献类型:
--
作者:
Chu, Eugene A.;Kim, Young J.

文献摘要

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喉癌是世界范围内第11位最常见的男性癌症,也是头颈部第二常见的恶性肿瘤。喉头的主要功能包括发声、呼吸和吞咽,但它也有助于味觉和嗅觉,因为它允许空气在特殊的感觉器官上流动。因此,喉部功能的丧失会影响说话和吞咽,以及一些让我们享受世界的感官。此外,全喉切除术绕过了上气消化道的关键湿化功能,这使得这些患者的肺部洗漱出现问题。自20世纪70年代以来,死亡率的变化相对较小,最近的研究不仅集中在提高生存率上,而且集中在喉保存方式上。
Laryngeal carcinoma is the eleventh-most common form of cancer among men worldwide and is the second-most common malignancy of the head and neck. The primary functions of the larynx involve phonation, respiration, and deglutition but it also contributes to taste and smell by allowing the movement of air over the special sense organs. Thus, loss of laryngeal function affects speech and swallowing and some of the senses that allow us to enjoy the world. Moreover, total laryngectomy bypasses the critical humidification function of the upper aerodigestive tract that renders pulmonary toiletry problematic for these patients. With relatively little change in mortality since the 1970s, recent research has focused not only on improving survival but on laryngeal preservation modalities.