Phosphatidylinositol 4-phosphate kinase is associated with the membrane skeleton in human erythrocytes.
Phosphatidylinositol 4-phosphate kinase is associated with the membrane skeleton in human erythrocytes.
复制标题
磷脂酰肌醇 4-磷酸激酶与人红细胞的膜骨架相关。
DOI:
10.1016/0006-291x(85)91859-5
复制
发表时间:
1985
影响因子:
3.1
通讯作者:
Dale,GL
中科院分区:
文献类型:
--
作者:
Dale,GL
Phosphatidylinositol 4-phosphate kinase was eluted from human erythrocyte stroma by three separate and distinct techniques which are known to disrupt the membrane skeleton. In addition, this kinase was found to be associated with the intact skeletons prepared by Triton X-100 extraction of stroma. Phosphatidylinositol 4-phosphate kinase which has been extracted from the membrane is a freely soluble protein with poor enzymatic activity toward added phosphatidylinositol-4-phosphate; however, the enzyme was shown to reassociate with skeleton-depleted stroma and then regain full enzymatic activity toward stromal bound substrate.