The association of refractive error, strabismus, and amblyopia with congenital ptosis

The association of refractive error, strabismus, and amblyopia with congenital ptosis
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DOI:
10.1016/j.jaapos.2011.08.006
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发表时间:
2011-12-01
期刊:
影响因子:
1.6
通讯作者:
Zobal-Ratner, Jitka
Zobal-Ratner, Jitka
中科院分区:
医学4区
文献类型:
--
作者:
Srinagesh, Vishwanath;Simon, John W.;Zobal-Ratner, Jitka

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目的了解先天性上睑下垂儿童弱视的发生率及其相关性。方法回顾性分析92例先天性上睑下垂患者的临床资料。主要的结局指标是相对上睑下垂的严重程度、斜视的存在和类型、屈光不正和弱视。结果92例患者中有22例(23.9%)存在弱视,几乎所有病例均伴有屈光参差或斜视,且上睑下垂更严重(P = 0.0001)。弱视更可能发生在眼睑相对不对称较大的病例中,而不发生在对称上睑下垂的儿童中。在一些病例中,屈光参差和弱视最初并不明显,但在随访期间逐渐发展。结论先天性上睑下垂患儿存在屈光参差和斜视性弱视的风险,并可能在发育早期发生进展。患者应定期检查,以评估和治疗这些潜在的并发症。([j]; 2011;15:541-544]
PURPOSE To determine the frequency of amblyopia and its associations among children with congenital ptosis.METHODS A retrospective chart review of 92 active patients with congenital ptosis in the practices of 2 of the authors. The main outcome measures were relative eyelid ptosis severity, presence and type of strabismus, refractive error, and amblyopia.RESULTS Amblyopia was identified in 22 of 92 patients (23.9%), in almost every case occurring in the context of coexisting anisometropia or strabismus and affecting the eye with the more severe ptosis (P = 0.0001). Amblvopia was more likely to occur in cases with greater relative eyelid asymmetry and did not develop in children with symmetric ptosis. In several cases, anisometropia and amblyopia were not initially apparent but progressively developed during follow-up.CONCLUSIONS Children with congenital ptosis are at risk of anisometropic and strabismic amblyopia, which may progress during early development. Patients should be examined at regular intervals to evaluate and treat these potential complications. (J AAPOS 2011;15:541-544)