Synthesis of N-alkyl and N-aryl isoquinolones and derivatives via Pd-catalysed C-H activation and cyclization reactions
Synthesis of N-alkyl and N-aryl isoquinolones and derivatives via Pd-catalysed C-H activation and cyclization reactions
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DOI：
10.1039/c2ob26668g
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发表时间：
2012-01-01
影响因子：
3.2
通讯作者：
Huang, Jianhui
中科院分区：
文献类型：
--
作者：
Zhang, Nana;Li, Binyao;Huang, Jianhui
Relatively less expensive Pd-catalysed oxidative coupling reactions for the preparation of N-alkyl and N-aryl substituted isoquinolones and their derivatives have been developed. A broad reaction scope has been demonstrated. In addition, studies of the reaction additives and mechanistic insights, as well as KIE studies for a better understanding of the reaction pathway, have been discussed.
