Effect of electrokinetic property of charged polyether sulfone membrane on bovine serum albumin fouling behavior
Effect of electrokinetic property of charged polyether sulfone membrane on bovine serum albumin fouling behavior
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DOI：
10.1007/s11783-017-0907-9
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发表时间：
2017-03
影响因子：
6.4
通讯作者：
Xiao-rong Meng;S. Huo;Lei Wang;Xu-dong Wang;Yong-tao Lv;Weiting Tang;Rui Miao;Dan-xi Huang
中科院分区：
文献类型：
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作者：
Xiao-rong Meng;S. Huo;Lei Wang;Xu-dong Wang;Yong-tao Lv;Weiting Tang;Rui Miao;Dan-xi Huang
采用本体化学改性和非溶剂诱导相分离法制备了带负电荷的羧甲基化聚醚砜（CMPES）和带正电荷的季铵盐化聚醚砜（qape）超滤膜。利用膜修饰胶体原子力显微镜（AFM）探针研究了聚醚砜（PES）膜界面电动力学特性对牛血清白蛋白（BSA）膜污染行为的影响。电动力学测试结果表明，QAPES膜的流动电位（ΔE）与其预期的diec值不一致，但在pH值为3 ~ 10的范围内，两种电荷修饰的PES膜的ζ电位比未修饰的膜更稳定。当pH值为3、4.7和9时，带电PES膜与BSA的相互作用行为表明，膜-BSA粘附力的跳距（F/R）与ζ电位绝对值之间存在显著的线性相关。带电改性显著降低了PES膜-BSA的附着力，附着力数据与BSA过滤过程中通量下降率呈良好的线性相关，特别是在CMPES膜上。以上实验事实证明，带电膜界面电双层结构及其电动力学性质与蛋白质膜的污染行为有着密切的联系。
Negatively charged carboxymethylated polyethersulfone (CMPES) and positively charged quaternized polyethersulfone (QAPES) ultrafiltration (UF) membranes were prepared by bulk chemical modification and non-solvent induced phase separation method. The effects of PES membrane interfacial electrokinetic property on the bovine serum albumin (BSA) membrane fouling behavior were studied with the aid of the membrane-modified colloidal atomic force microscopy (AFM) probe. Electrokinetic test results indicated that the streaming potential (ΔE) of QAPES membrane was not consistent with its expectedIECvalue, however, within the pH range of 3–10, theζpotentials of two charged-modified PES membranes were more stable than the unmodified membrane. When pH value was 3, 4.7 or 9, the interaction behavior between charged PES membrane and BSA showed that there was significant linear correlation between the jump distancer0of membrane-BSA adhesion force (F/R) and theζpotential absolute value. Charged modification significantly reduced the adhesion of PES membrane-BSA, and the adhesion data was good linear correlated with the flux decline rate in BSA filtration process, especially reflected in the CMPES membrane. The above experimental facts proved that the charged membrane interfacial electric double layer structure and its electrokinetic property had strong ties with the protein membrane fouling behavior.