DIAGNOSIS OF INFECTION BY FROZEN-SECTION DURING REVISION ARTHROPLASTY
DIAGNOSIS OF INFECTION BY FROZEN-SECTION DURING REVISION ARTHROPLASTY
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DOI：
10.1302/0301-620x.77b1.7822391
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发表时间：
1995-01-01
影响因子：
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通讯作者：
SMITH, PM
中科院分区：
文献类型：
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作者：
ATHANASOU, NA;PANDEY, R;SMITH, PM
我们评估术中冰冻切片组织学检测106个髋关节和膝关节置换失败的感染的有效性。我们发现炎症变化与感染一致(在几个样本中平均每个高倍视野有一个或多个中性粒细胞或浆细胞)；20例在细菌培养上有显著增长，与细菌培养相比，冰冻切片提供两个假阴性结果和三个假阳性结果(敏感性，90%；特异性，96%；和准确性，95%)。阳性预测值为88%，阴性预测值为98%。这些结果支持将术中冰冻切片组织学包括在任何松动假体翻修术的方案中。
We assessed the efficacy of intraoperative frozen-section histology in detecting infection in failed arthroplasties in 106 hips and knees.We found inflammatory changes consistent with infection (an average of one or more neutrophil polymorphs or plasma cells per high-power field in several samples) in 18 cases; there was a significant growth on bacterial culture in 20 cases, Compared with the bacterial cultures, the frozen sections provided two false-negative results and three false-positive results (sensitivity, 90%; specificity, 96%; and accuracy, 95%). The positive predictive value was 88%, the negative value, 98%.These results support the inclusion of intra-operative frozen-section histology in any protocol for revision arthroplasty for loose components.