Alcohol Use Accelerates HIV Disease Progression
Alcohol Use Accelerates HIV Disease Progression
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DOI：
10.1089/aid.2009.0211
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发表时间：
2010-05-01
影响因子：
1.5
通讯作者：
Campa, Adriana
中科院分区：
文献类型：
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作者：
Baum, Marianna K.;Rafie, Carlin;Campa, Adriana
酒精滥用对艾滋病毒疾病进展的影响尚未明确确定。对231名HIV阳性成人进行了一项为期30个月的前瞻性纵向研究，包括酒精和非法药物使用史、抗逆转录病毒治疗（ART）依从性、CD 4（+）细胞计数和每6个月一次的HIV病毒载量。频繁饮酒者（每天两次或两次以上饮酒）的CD 4下降可能性比正常人高2.91倍（95% CI：1.23-6.85，p=0.015），
The effects of alcohol abuse on HIV disease progression have not been definitively established. A prospective, 30-month, longitudinal study of 231 HIV+ adults included history of alcohol and illicit drug use, adherence to antiretroviral therapy (ART), CD4(+) cell count, and HIV viral load every 6 months. Frequent alcohol users (two or more drinks daily) were 2.91 times (95% CI: 1.23-6.85, p=0.015) more likely to present a decline of CD4 to