Does pulmonary valve replacement post repair of tetralogy of Fallot improve right ventricular function?
Does pulmonary valve replacement post repair of tetralogy of Fallot improve right ventricular function?
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DOI：
10.1510/icvts.2009.211011
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发表时间：
2009-09-01
影响因子：
--
通讯作者：
Haw, Marcus P
中科院分区：
文献类型：
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作者：
Adamson, Louise;Vohra, Hunaid A;Haw, Marcus P
心脏外科的最佳证据主题是根据一个结构化的协议编写的。研究的问题是，法洛四联症修复后肺动脉瓣置换术（PVR）是否改善了包括右心室（RV）功能在内的预后。使用下面提到的搜索，共确定了730篇相关论文，其中19篇论文代表了回答这个问题的最佳证据。将作者、期刊、发表日期和国家、研究的患者组、研究类型、相关结果、结果和研究的不足列成表格。我们的结论是，法洛四联症修复后的PVR已被证明可以改善右心室功能并提供症状性益处。几项回顾性综述报告了左室舒张末期和收缩末期体积的持续减少和左室卒中容量的改善，一项研究也发现左室卒中容量的改善。在这一人群中，PVR似乎可以改善临床结果，并且可以以低死亡率进行。
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether pulmonary valve replacement (PVR) after repair of tetralogy of Fallot improved outcomes including right ventricular (RV) function. Altogether 730 relevant papers were identified using the below mentioned search, 19 papers represented the best evidence to answer the question. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses were tabulated. We conclude that PVR after tetralogy of Fallot repair has been shown to improve RV function and to offer symptomatic benefit. Several retrospective reviews report consistent reductions in RV end diastolic and systolic volumes and improvement in RV stroke volume, with one study also finding improvement in left ventricular stroke volume. PVR in this population appears to result in improved clinical outcome and can be performed with low mortality.