Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US
Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US
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DOI：
10.1111/j.1753-0407.2010.00078.x
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发表时间：
2010-09-01
影响因子：
4.5
通讯作者：
Zhao, Guixiang
中科院分区：
文献类型：
--
作者：
Ford, Earl S.;Li, Chaoyang;Zhao, Guixiang
背景：最近，一份联合科学声明弥合了以前代谢综合征定义之间的差异。我们的目的是估计代谢综合征的患病率在美国成年人的代表性样本，并检查其correlateds.Methods：我们分析了2003-2006年全国健康和营养检查调查的3461名年龄≥ 20岁的参与者的数据。以男性腰围102 cm和女性腰围≥ 88 cm为阈值，年龄调整后的代谢综合征患病率在所有成年人中为34.3%，男性为36.1%，女性为32.4%。使用国际糖尿病联合会针对种族或民族的腰围标准，所有参与者的代谢综合征年龄调整患病率为38.5%，男性为41.9%，女性为35.0%。患病率随年龄增长而增加，在60-69岁之间达到高峰。非裔美国男性的患病率低于白色或墨西哥裔美国男性，白色女性的患病率低于非裔美国或墨西哥裔美国女性。在多变量回归模型中，注意到年龄（阳性）、性别（男性高于女性）、种族或民族（非裔美国人和另一种族的参与者低于白人）、教育状况（相反）、高胆固醇血症（阳性）、C反应蛋白浓度（阳性）、休闲时间体力活动（相反）、微量白蛋白尿（阳性）和高胰岛素血症（阳性）。身体质量指数的额外调整削弱了许多协会，教育状况和微量白蛋白尿不再显着的贡献者model.Conclusion：代谢综合征仍然是高度流行的成年人在美国。
Background: Recently, a Joint Scientific Statement bridged differences between previous definitions of metabolic syndrome. Our objective was to estimate the prevalence of metabolic syndrome in a representative sample of US adults and to examine its correlates.Methods: We analyzed data for up to 3461 participants aged >= 20 years of the 2003-2006 National Health and Nutrition Examination Survey.Results: Using waist circumference thresholds of 102 cm for men and >= 88 cm for women, the age-adjusted prevalence of metabolic syndrome was 34.3% among all adults, 36.1% among men, and 32.4% among women. Using racial- or ethnic-specific International Diabetes Federation criteria for waist circumference, the age-adjusted prevalence of metabolic syndrome was 38.5% for all participants, 41.9% for men, and 35.0% for women. Prevalence increased with age, peaking among those aged 60-69 years. Prevalence was lower among African American men than White or Mexican American men, and lower among White women than among African American or Mexican American women. In a multivariate regression model, significant independent associations were noted for age (positive), gender (men higher than women), race or ethnicity (African Americans and participants of another race lower than Whites), educational status (inverse), hypercholesterolemia (positive), concentrations of C-reactive protein (positive), leisure time physical activity (inverse), microalbuminuria (positive), and hyperinsulinemia (positive). Additional adjustment for body mass index weakened many of the associations, with educational status and microalbuminuria no longer significant contributors to the model.Conclusion: Metabolic syndrome continues to be highly prevalent among adults in the US.