A potentiometric tattoo sensor for monitoring ammonium in sweat
A potentiometric tattoo sensor for monitoring ammonium in sweat
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DOI：
10.1039/c3an01672b
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发表时间：
2013-01-01
期刊：
影响因子：
4.2
通讯作者：
Wang, Joseph
中科院分区：
文献类型：
--
作者：
Guinovart, Tomas;Bandodkar, Amay J.;Wang, Joseph
介绍了一种用于监测汗液中铵水平的临时转移纹身平台的新型离子选择性电位计电池的开发和分析表征。这种皮肤磨损传感器的制造基于丝网印刷设计，结合了全固态电位传感器技术，用于工作电极和参考电极，连接到基于非动蛋白离子载体的氨选择性聚合物膜。由此产生的纹身电位传感器的工作范围在10(-4)M到0.1 M之间，完全符合汗液中铵的生理水平。在表皮预期的严格机械应力下进行的测试表明，分析性能不受拉伸或弯曲等因素的影响。由于铵的水平与蛋白质的分解有关，新的可穿戴电位纹身传感器为监测运动表现或检测医疗保健中的代谢紊乱提供了相当大的希望。这种表皮整合、丝网印刷技术和电位传感的结合代表了对人体汗液中各种电解质进行无创监测的诱人途径。
The development and analytical characterization of a novel ion-selective potentiometric cell in a temporary-transfer tattoo platform for monitoring ammonium levels in sweat is presented. The fabrication of this skin-worn sensor, which is based on a screen-printed design, incorporates all-solid-state potentiometric sensor technology for both the working and reference electrodes, in connection to ammonium-selective polymeric membrane based on the nonactin ionophore. The resulting tattooed potentiometric sensor exhibits a working range between 10(-4) M to 0.1 M, well within the physiological levels of ammonium in sweat. Testing under stringent mechanical stress expected on the epidermis shows that the analytical performance is not affected by factors such as stretching or bending. Since the levels of ammonium are related to the breakdown of proteins, the new wearable potentiometric tattoo sensor offers considerable promise for monitoring sport performance or detecting metabolic disorders in healthcare. Such combination of the epidermal integration, screen-printed technology and potentiometric sensing represents an attractive path towards non-invasive monitoring of a variety of electrolytes in human perspiration.