JOY: protein sequence-structure representation and analysis

JOY: protein sequence-structure representation and analysis
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DOI:
10.1093/bioinformatics/14.7.617
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发表时间:
1998-01-01
期刊:
影响因子:
5.8
通讯作者:
Overingon, JP
Overingon, JP
中科院分区:
生物学3区
文献类型:
--
作者:
Mizuguchi, K;Deane, CM;Overingon, JP

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动机:JOY 是一个用三维 (3D) 结构特征注释蛋白质序列比对的程序。它的开发目的是在序列比对中显示 3D 结构信息,并帮助了解氨基酸在其特定局部环境中的保守性。结果:JOY 表示现在构成两个蛋白质结构比对数据库的重要组成部分。 HOMSTRAD(http://www-cryst.bioc.cam.ac.uk/类似于homstrad)和CAMPASS(http://www-cryst.bioc.cam.ac.uk/类似于campass)。它还已成功用于识别远距离进化关系。 可用性:可以通过匿名 ftp 从 torsa.bioc.cam.ac.uk 目录 /pub/joy/ 获取该程序。 JOY 下水道的地址是http://www-cryst。 bioc.cam.ac.uk/cgi-bin/joy.cgi.联系方式:kenji@cryst.bioc.cam.ac.uk。
Motivation: JOY is a program to annotate protein sequence alignments with three-dimensional (3D) structural features. It was developed to display 3D structural information in a sequence alignment and to help understand the conservation of amino acids in their specific local environments.Results: The JOY representation now constitutes an essential part of the two databases of protein structure alignments. HOMSTRAD (http://www-cryst.bioc.cam.ac.uk/similar to homstrad) and CAMPASS (http://www-cryst.bioc.cam.ac.uk/similar to campass). It has also been successfully used for identifying distant evolutionary relationships.Availability: The program can be obtained via anonymous ftp from torsa.bioc.cam.ac.uk fi om the directory /pub/joy/. The address for the JOY sewer is http://www-cryst. bioc.cam.ac.uk/cgi-bin/joy.cgi.Contact: kenji@cryst.bioc.cam.ac.uk.