Influence of Age on the Hemodynamic Response to Exercise

Influence of Age on the Hemodynamic Response to Exercise
复制标题

年龄对运动血流动力学反应的影响

DOI:
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发表时间:
1967
期刊:
影响因子:
37.8
通讯作者:
J. Conway
J. Conway
中科院分区:
医学1区
文献类型:
--
作者:
S. Julius;A. Amery;L. Whitlock;J. Conway

文献摘要

被引文献

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呼吸和血流动力学测量54名久坐不动的受试者在渐进式运动的自行车测力计的最大自愿努力点。该组的年龄范围为18至68岁。最大耐受运动量,即最高达到的耗氧量(Vo2)水平,随年龄的增长而减少。老年受试者的静息心输出量(Q)低于正常受试者,但Q随Vo2的增加而增加。没有证据表明,当老年受试者接近最高运动负荷时,该曲线变平。因此,动静脉氧差在高负荷时没有异常增加,老年受试者对运动的心脏反应似乎是足够的。在次最大负荷下,吸入空气量和心率与Vo2之间的关系不受年龄的影响。随着运动,收缩压逐渐增加,老年受试者的变化更大。静息时外周总阻力随年龄增长而增加,但随着运动量的增加,这种差异逐渐减小。
Respiratory and hemodynamic measurements were made on 54 sedentary subjects during progressive exercise on a bicycle ergometer up to the point of maximal voluntary effort. The age range of the group was from 18 to 68 years.The maximum tolerated exercise, as indicated by the highest achieved level of oxygen consumption (Vo2), diminished with age. Older subjects had a lower resting cardiac output (Q) than normal subjects, but an identical increase in Q with Vo2. There was no evidence of flattening of this curve as the older subjects approached highest exercise loads. Consequently, the arteriovenous oxygen difference did not increase abnormally on high loads, and the cardiac response to exercise in older subjects appeared to be adequate. The relationship between inspired air volume and heart rate with Vo2 at submaximal loads was not influenced by age.Systolic pressure increased progressively with exercise and showed a greater change in older subjects. Total peripheral resistance at rest increased with age; but with increasing exercise, this difference progressively diminished.