ENZYME-CATALYSED CONJUGATIONS OF GLUTATHIONE WITH UNSATURATED COMPOUNDS
ENZYME-CATALYSED CONJUGATIONS OF GLUTATHIONE WITH UNSATURATED COMPOUNDS
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DOI：
10.1042/bj1040095
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发表时间：
1967-01-01
影响因子：
4.1
通讯作者：
CHASSEAUD, LF
中科院分区：
文献类型：
--
作者：
BOYLAND, E;CHASSEAUD, LF
大鼠肝上清催化马来酸二乙酯与谷胱甘肽的反应。证据表明所涉及的酶不同于已知的谷胱甘肽偶联酶，谷胱甘肽s -烷基转移酶，s -芳基转移酶和s -环氧化物转移酶。大鼠肝上清催化许多其他[α][β] -不饱和化合物（包括醛、酮、内酯、腈和硝基化合物）与谷胱甘肽的反应：单独的酶可能负责这些反应。
Rat-liver supernatant catalyses the reaction of diethyl maleate with glutathione. Evidence is presented that the enzyme involved is different from the known glutathione-conjugating enzymes, glutathione S-alkyltransferase, S-aryltransferase and S-epoxidetransferase. Rat-liver supernatant catalyses the reaction of a number of other [alpha][beta] -unsaturated compounds, including aldehydes, ketones, lactones, nitriles and nitro compounds, with glutathione: separate enzymes may be responsible for these reactions.