Chiral amine-thioureas bearing multiple hydrogen bonding donors: highly efficient organocatalysts for asymmetric Michael addition of acetylacetone to nitroolefins.
Chiral amine-thioureas bearing multiple hydrogen bonding donors: highly efficient organocatalysts for asymmetric Michael addition of acetylacetone to nitroolefins.
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DOI：
10.1039/b718949d
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发表时间：
2008-03
影响因子：
4.9
通讯作者：
Chun‐Jiang Wang;Zhi-Hai Zhang;Xiuqin Dong;Xiaojun Wu
中科院分区：
文献类型：
--
作者：
Chun‐Jiang Wang;Zhi-Hai Zhang;Xiuqin Dong;Xiaojun Wu
New bifunctional organocatalysts amine-thioureas bearing multiple hydrogen bonding donors were synthesized and applied in catalytic asymmetric Michael addition of acetylacetone to aryl and alkyl nitroolefins. Multiple hydrogen bonding donors play a significant role in accelerating reactions, improving yields and enantioselectivities.
