SPATIAL MEMORY DEFICIT IN SENESCENT RATS
SPATIAL MEMORY DEFICIT IN SENESCENT RATS
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DOI：
10.1037/h0081022
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发表时间：
1980-01-01
期刊：
影响因子：
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通讯作者：
HONIG, WK
中科院分区：
文献类型：
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作者：
BARNES, CA;NADEL, L;HONIG, WK
衰老组（29个月）的空间记忆能力较对照组（29个月）差。和中年（14个月）Long Evans大鼠采用3种任务进行研究。在第一阶段，老鼠被要求从一个圆形平台的明亮表面移动到一个黑暗的隧道中，隧道周围有18个洞。第二个任务分离了偏好策略（即，提示，反应位置）。第三个任务涉及对环境中特定位置的记忆，使用水奖励来诱导在径向8臂迷宫上运行。衰老率表现出较差的记忆奖励的地方和证据表明，这可能是由于使用效率较低的性能策略，因为在空间记忆的赤字。
The spatial memory of senescent (29 mo.) and middle-aged (14 mo.) Long Evans rats was investigated using 3 tasks. In the 1st, rats were required to move from the brightly lit surface of a circular platform into a dark tunnel under 1 of 18 holes lining its circumference. The 2nd task dissociated the strategy of preference (i.e., cue, response place) of these rats in a 2 choice (T-maze) discrimination problem. The 3rd task involved memory for specific places in the environment, with the use of water reward to induce running on a radial 8-arm maze. The senescent rates exhibited poorer memory for rewarded places and evidence is presented that this may be a result of using less efficient performance strategies because of a deficit in spatial memory.