Deviant gaze processing in children with autism: an ERP study
Deviant gaze processing in children with autism: an ERP study
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DOI：
10.1016/j.neuropsychologia.2004.12.002
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发表时间：
2005-01-01
期刊：
影响因子：
2.6
通讯作者：
Hasegawa, T
中科院分区：
文献类型：
--
作者：
Senju, A;Tojo, Y;Hasegawa, T
本研究探讨了事件相关电位（ERP）在一个古怪的任务，其中检测特定的眼睛方向是需要的儿童与非自闭症。检测到眼睛方向的变化会引起枕颞部的负性，这在自闭症儿童和非自闭症儿童之间有两个主要区别。首先，虽然这种枕-颞负性在发育正常的儿童的右半球占主导地位。在自闭症儿童中，它在两侧均匀分布。第二，这种消极的幅度是更明显的，在典型的发达国家的儿童相比，转移目光的直接注视的检测，但不敏感的直接/转移目光的方向在自闭症儿童，这与行为报告收敛。结果与以往文献一致，提示右半球，特别是上级颞沟，在凝视加工中的重要性。结果表明，异常的神经基板可能参与自闭症患者的注视处理。(c)2005爱思唯尔有限公司保留所有权利。
This study investigated event-related potentials (ERP) during an oddball task in which detection of specific eye direction was required of children with and without autism. The detection of a change in eye direction elicited occipito-temporal negativity, which had two major differences between children with and without autism. First, while this occipito-temporal negativity predominated in the right hemisphere of typically developed children. it was distributed equally bilaterally in children with autism. Second, the amplitude of this negativity was more pronounced in typically developed children in response to the detection of direct gaze as compared to averted gaze, but was not sensitive to direct/averted gaze direction in children with autism, which converges with behavioral reports. The results concur with previous literature, suggesting the importance of the right hemisphere, especially the superior temporal sulcus, in gaze processing. Results indicate that deviant neural substrates might be involved in gaze processing in individuals with autism. (c) 2005 Elsevier Ltd. All rights reserved.