Fission yeast gene structure and recognition.
Fission yeast gene structure and recognition.
复制标题
裂殖酵母基因结构和识别。
DOI：
10.1093/nar/22.9.1750
复制
发表时间：
1994
影响因子：
14.9
通讯作者：
Marr,TG
中科院分区：
文献类型：
--
作者：
Zhang,MQ;Marr,TG
从GenBank(版本号81.0)中提取了210个庞贝裂殖酵母DNA序列(524,794bp)的数据库，并通过多种方法进行了检查，以表征这些序列的统计特征，这些序列可能作为信使RNA剪接的信号或约束。编制的统计信息包括剪接信号(供体、受体和分支位点)图谱、翻译起始图谱、外显子/内含子长度分布、ORF分布、CDS大小分布、密码子使用表和6-字节组分布。给出了各种信号的信息内容。一个基于规则的交互式计算机程序INTRON.PLOT已经被开发出来，并成功地分析了7个新测序的基因。
A database of 210Schizosaccharomyces pombeDNA sequences (524,794 bp) was extracted from GenBank (release number 81.0) and examined by a number of methods in order to characterize statistical features of these sequences that might serve as signals or constraints for messenger RNA splicing. The statistical information compiled includes splicing signal (donor, acceptor and branch site) profiles, translational initiation start profile, exon/intron length distributions, ORF distribution, CDS size distribution, codon usage table, and 6-tuple distribution. The information content of the various signals are also presented. A rule-based interactive computer program for finding introns called INTRON.PLOT has been developed and was used to successfully analyze 7 newly sequenced genes.