Miniaturized Fully Passive Wireless Neural Recording With Heterogeneous Integration in Thin Packages
Miniaturized Fully Passive Wireless Neural Recording With Heterogeneous Integration in Thin Packages
复制标题
DOI：
10.1109/tcpmt.2023.3253844
复制
发表时间：
2023-03-01
影响因子：
2.2
通讯作者：
Raj, Pulugurtha Markondeya
中科院分区：
文献类型：
--
作者：
Been Sayeed, Sk Yeahia;Venkatakrishnan, Satheesh Bojja;Raj, Pulugurtha Markondeya
无线全被动神经记录系统与异构集成的传感，混合和通信组件在柔性聚合物介电薄膜。记录神经传感器具有天线、反并联二极管和旁路电容器，以用神经电位调制输入载波信号并将混合信号反向散射到外部读取器电路。平面天线是在低介电常数的液晶聚合物柔性基板上实现的。所设计的天线拓扑结构是实现与一个单一的金属层，消除了对基板厚度的依赖，并导致更薄的传感器。这是一个主要的进步相比，现有的被动神经记录与刚性和较厚的基板和组件。与早期研究相比，大约实现了80%的厚度减少和20%的体积减少，具有相似的性能。因此，我们的方法导致低成本和一次性的无线神经传感器在一个灵活的平台与异构集成。因此，本文在三个方面推进了创新的无线神经记录：1）用于无源遥测的小型化神经记录的先进封装，通过这种封装，传感器的整体尺寸减小而不会降低性能; 2）用于神经记录应用的新天线拓扑结构;以及3）详细的功率链路分析，以估计最小信号灵敏度。
Wireless fully passive neural recording systems are demonstrated with heterogeneous integration of sensing, mixing, and communication components in flexible polymer dielectric films. The recording neurosensor has an antenna, antiparallel diode, and a bypass capacitor to modulate an incoming carrier signal with the neuropotentials and backscatter the mixed signal to an external reader circuit. Planar antennas are realized on liquid crystal polymer (LCP) flexible substrates with low dielectric constant. The designed antenna topology is realized with a single metal layer and eliminates the dependency on substrate thickness, and leads to thinner sensors. This is a major advance compared to prior passive neural recording with rigid and thicker substrates and components. Approximately, 80% thickness reduction and 20% volume reduction are achieved with a similar performance when compared to earlier studies. Our approach thus leads to low-cost and disposable wireless neurosensors on a flexible platform with heterogeneous integration. This article thus advances innovative wireless neural recording in three aspects: 1)advanced packaging for miniaturized neural recording with passive telemetry, through which the overall size of the sensor is reduced without degrading the performance; 2) new antenna topologies for neural recording applications; and 3) detailed power link analysis to estimate the minimum signal sensitivity.